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Olanib 150 mg (Olaparib) Capsules

Olanib 150 mg (Olaparib) Capsules

Generic: Olaparib
Strength150 mg
Pack Size112 Capsules
Dosage FormCapsule
ManufacturerEverest Pharmaceuticals Ltd.
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Uses & Therapeutic Effects
  • Ovarian Cancer: Used as maintenance treatment in selected patients with advanced ovarian, fallopian tube, or primary peritoneal cancer.
  • Breast Cancer: May be used for certain HER2-negative breast cancers with specific inherited or tumor-related BRCA mutations.
  • Pancreatic Cancer: Used as maintenance therapy for selected patients with metastatic pancreatic cancer associated with germline BRCA mutations.
  • Prostate Cancer: Used for certain advanced prostate cancers with specific homologous recombination repair (HRR) gene alterations.
  • Maintenance Therapy: Helps delay disease progression in appropriate patients after an initial response or stable disease with previous treatment.
  • Targeted Cancer Therapy: Olaparib works by interfering with DNA-repair processes in cancer cells, particularly cells that already have defects in other DNA-repair pathways.

Therapeutic Effect: By blocking PARP enzymes, olaparib increases DNA damage within susceptible cancer cells. Cells with certain DNA-repair deficiencies may be unable to repair this damage effectively, which can lead to cancer-cell death or slowed tumor growth.

Ingredients & Composition

Active Ingredient:

  • Olaparib 50 mg

Pharmaceutical Class:

  • Poly(ADP-ribose) polymerase (PARP) inhibitor
  • Antineoplastic / targeted anticancer agent

Dosage Form:

  • Oral capsule

Composition:
Each capsule contains Olaparib 50 mg as the active pharmaceutical ingredient. The formulation may also contain inactive pharmaceutical excipients required for capsule manufacture, stability, and product performance. The exact excipient composition should be confirmed from the official product packaging or package insert.

Dosage & Administration

  • Route: Oral administration.
  • Usual Adult Dose: The commonly recommended olaparib dose for several approved indications is 300 mg twice daily, but the appropriate dose depends on the cancer type, treatment regimen, kidney function, concomitant medicines, and individual patient factors.
  • For 50 mg Capsules: The number of capsules required to achieve the prescribed dose depends on the treating physician's regimen. Do not determine the capsule quantity yourself.
  • Take olaparib exactly as prescribed by the oncologist or healthcare professional.
  • Doses are generally taken at approximately 12-hour intervals.
  • Capsules should be swallowed whole with water. Do not open, crush, dissolve, or chew the capsules.
  • Olaparib may generally be taken with or without food, according to the prescribing information for the specific formulation.
  • Take the medicine at approximately the same times each day to maintain consistent drug exposure.
  • Continue treatment for the duration recommended by the treating physician unless treatment is stopped or modified because of disease progression, adverse effects, or another clinical reason.

Missed Dose

If a dose is missed, do not take an extra dose to compensate. Take the next scheduled dose at its usual time and continue the prescribed treatment schedule.

Important Administration Instructions

  • Do not change the dose without medical supervision.
  • Do not stop treatment abruptly unless instructed by your healthcare professional.
  • Dose interruption or reduction may be necessary when significant adverse reactions occur.
  • Patients taking medicines that strongly affect CYP3A enzymes may require special dose consideration.
  • Kidney and liver function may need to be assessed before and during treatment.
  • Regular blood tests may be required to monitor blood-cell counts and detect treatment-related abnormalities.
  • Because olaparib is a prescription anticancer medicine, treatment should be individualized according to the patient's diagnosis, genetic/biomarker status, previous therapies, and overall clinical condition.
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General Safety Advice
Pregnancy
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Please consult your physician before consuming any medicine during pregnancy.

Breastfeeding
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Discuss with your doctor to understand the risks and benefits.

Alcohol
Caution

Avoid consuming alcohol as it may cause adverse interactions with medications.

Driving
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Check if your medicine causes drowsiness before driving or operating machinery.

Medical Disclaimer: The primary intention of this platform is to ensure that consumers get information that is accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine.
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