Olanib 150 mg (Olaparib) Capsules

Olanib 150 mg contains Olaparib, a targeted anticancer medicine belonging to the PARP inhibitor class. It is used in selected patients with specific types of cancer and appropriate clinical or molecular characteristics. Treatment decisions are made according to the cancer type, disease stage, previous treatment, biomarker status and the prescribing oncologist’s assessment.

Therapeutic Uses

• Used in selected cases of ovarian cancer, including certain advanced or recurrent disease settings.
• May be prescribed for fallopian tube cancer and primary peritoneal cancer in appropriate patients.
• Used in specific patients with HER2-negative breast cancer when relevant genetic or clinical criteria are met.
• May be used as part of treatment strategies for selected pancreatic cancer patients with appropriate germline BRCA-related disease.
• Used in certain metastatic castration-resistant prostate cancer cases with specific homologous recombination repair-related genetic alterations.
• Depending on the indication, Olaparib may be prescribed as maintenance therapy after a response or stable disease following previous treatment.
• It may also be used in combination with another anticancer treatment in specific approved clinical settings.

Therapeutic Effects

Olaparib works by inhibiting PARP-1 and PARP-2 enzymes, which are involved in repairing damaged DNA. Blocking these enzymes makes it more difficult for certain cancer cells with defective DNA-repair pathways to survive. This can contribute to cancer-cell death and help delay disease progression in appropriately selected patients.

Important: Olaparib is not suitable for every cancer patient. Genetic testing, cancer type, previous treatment and overall clinical condition may influence whether this medicine is appropriate.

Active Ingredient

Olaparib 150 mg

Dosage Form

Film-Coated Tablet

Pharmaceutical Class

PARP (Poly ADP-Ribose Polymerase) Inhibitor

Composition

Each tablet contains:

• Olaparib BP/Pharmaceutical Grade – 150 mg
• Other inactive ingredients/excipients are used to provide the tablet with its required structure, stability, coating and manufacturing characteristics.

The exact list of excipients may vary according to the specific formulation and manufacturer. Patients with known allergies or sensitivities should review the product-specific ingredient information before use.

Active Ingredient Function

Olaparib is the pharmacologically active component responsible for the medicine's therapeutic effect. It inhibits PARP enzymes involved in DNA damage repair and is particularly relevant in cancers where alternative DNA-repair mechanisms are already compromised.