Crizona 250 mg (Crizotinib) Capsules

Crizona 250 contains Crizotinib, a targeted anticancer medicine used to treat specific types of cancer with identifiable genetic alterations. It works by blocking abnormal proteins that promote cancer cell growth and spread, helping to slow disease progression. Treatment is recommended only after appropriate biomarker testing and under the supervision of an experienced oncologist.

Therapeutic Uses

• Treatment of ALK-positive advanced or metastatic non-small cell lung cancer (NSCLC)
• Treatment of ROS1-positive advanced or metastatic NSCLC
• Management of selected tumors with MET gene alterations, where clinically appropriate
• Precision oncology treatment based on approved molecular testing

Therapeutic Effects

• Slows the growth and spread of cancer cells
• Targets abnormal ALK and ROS1 signaling pathways
• Helps delay disease progression
• May improve progression-free survival in eligible patients
• Supports personalized cancer treatment based on genetic biomarkers 

Active Ingredient

Crizotinib INN 250 mg

Composition

Each hard gelatin capsule contains:

• Active Ingredient: Crizotinib INN 250 mg
• Dosage Form: Oral Capsule
• Strength: 250 mg

Pharmacological Class: Targeted Anticancer Agent (Tyrosine Kinase Inhibitor)

Always use Crizona 250 exactly as prescribed by a qualified healthcare professional. Dosage may vary depending on the patient's medical condition, treatment response, and tolerability.

Recommended Adult Dose

• 250 mg orally twice daily (approximately every 12 hours), or as directed by the treating oncologist.

Administration Instructions

• Swallow the capsule whole with water.
• Do not crush, chew, or open the capsule.
• It may be taken with or without food.
• Take doses at the same times each day to maintain consistent drug levels.

Missed Dose

• If a dose is missed, take it as soon as remembered unless the next scheduled dose is due within 6 hours.
• Do not take two doses together to make up for a missed dose.

Dose Adjustments

Your healthcare provider may reduce, interrupt, or discontinue treatment if significant side effects occur, including liver toxicity, heart rhythm abnormalities, or severe gastrointestinal reactions.

Important Administration Advice

• Use only under the supervision of an oncologist.
• Regular monitoring of liver function, blood counts, vision, and heart rhythm may be required during treatment.
• Do not stop taking the medicine without consulting your healthcare provider.

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